Advances in technology, especially those involving artificial intelligence and genetic sequencing, are moving rapidly toward an inflection point that will change the nature of business, healthcare, employment and human longevity in very specific ways. It is imperative that academic and business professionals fully absorb the nature of the coming changes for it is certain that "the bells toll for thee." This presentation will focus specifically on the major technologies of today that are laying a foundation for a series of technologies that will make the innovations of the late 19th century and all of the innovations of the 20th century look like mere tinkering. The presentation will be presented in an interactive way with the individuals sitting in on the session.