This study investigates the impact of economic policy on long-term growth in Cameroon. The study isolates growth that results from accumulation of factors from that resulting from the quality of those factors, which in turn depends on government policies and human capital accumulation. This is critical in guiding the implementation of medium and long-term growth strategies of the country. In order to achieve this, we employed econometric techniques on time series data for the period from 1978 to 2014. The study covered a period of time when Cameroon’s economic performance was mixed: a decline, then some recovery, albeit sluggish since the mid-1990s, hence the need to disentangle the contribution of policies to growth from that arising from factor accumulation. Before estimating the growth equation, the characteristics of the data was examined to determine whether the data was stationary or not, and also to determine the order of integration. The results from the error correction model show that capital is a robust determinant of economic growth in Cameroon. The results further reveal that higher levels of inflation rates are harmful to economic growth in the country. These results suggest the need for prudent policies especially well implemented macroeconomic policies that can positively affect economic growth in Cameroon.